Severe deep white matter lesions and outcome in elderly patients with major depressive disorder: follow up study.

@article{OBrien1998SevereDW,
  title={Severe deep white matter lesions and outcome in elderly patients with major depressive disorder: follow up study.},
  author={John T. O'Brien and David J Ames and Ernest Chiu and Isaac Schweitzer and Patricia Desmond and Brian M. Tress},
  journal={BMJ},
  year={1998},
  volume={317 7164},
  pages={
          982-4
        }
}
OBJECTIVE To determine the difference in outcome among elderly people with major depression who do and do not have severe white matter lesions on magnetic resonance imaging. DESIGN Follow up study. SETTING Two psychiatric and two general hospitals in Melbourne, Australia. SUBJECTS 60 depressed subjects aged over 55 referred to hospital psychiatric services with major depressive disorder meeting American Psychiatric Association (DSM-IIIR) criteria. MAIN OUTCOME MEASURE Proportion with… CONTINUE READING
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