Severe combined immunodeficiency disease: a pathological analysis of 26 cases.

@article{Gosseye1983SevereCI,
  title={Severe combined immunodeficiency disease: a pathological analysis of 26 cases.},
  author={Serge Gosseye and Nicole Diebold and Claude Griscelli and Christian Nezelof},
  journal={Clinical immunology and immunopathology},
  year={1983},
  volume={29 1},
  pages={58-77}
}
Autopsy material and clinical information were analyzed in 25 cases of untreated or unsuccessfully treated severe combined immunodeficiency disease and one case successfully treated by bone marrow grafting. Two cases were adenosine deaminase deficient and one was nucleoside phosphorylase deficient. The histological appearance of the thymus fell into four clearly recognizable patterns: simple dysplasia, dysplasia with corticomedullary differentiation, dysplasia with pseudoglandular appearance… CONTINUE READING

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