Severe chronic allergic (and related) diseases: a uniform approach--a MeDALL--GA2LEN--ARIA position paper.

@article{Bousquet2012SevereCA,
  title={Severe chronic allergic (and related) diseases: a uniform approach--a MeDALL--GA2LEN--ARIA position paper.},
  author={Jean Bousquet and Joseph Maria Ant{\'o} and Pascal Demoly and Holger J. Sch{\"u}nemann and Alkis G. Togias and M{\"u}beccel Akdis and Charles Auffray and Claus Bachert and Thomas Bieber and Philippe Jean Bousquet and K H Carlsen and T B Casale and {\'A}lvaro Augusto Cruz and T. Keil and Karin C Lodrup Carlsen and Marsha Maurer and K. Ohta and Nikolaos G. Papadopoulos and Miguel Rom{\'a}n Rodr{\'i}guez and Boleslaw Samolinski and Ioana Agache and Ange Andrianarisoa and Chee Siang Ang and Isabella Annesi-Maesano and Ferran Ballester and Carlos Eduardo Baena-Cagnani and Xavier Basaga{\~n}a and Eric D Bateman and Elizabeth H Bel and Anna Bedbrook and Bianca Begh{\'e} and Majed B{\'e}ji and Ali Ben Kheder and Marta Benet and K Saifuddin Bennoor and K. C. Bergmann and F Berrissoul and C Bindslev Jensen and Eugene Bleecker and Sergio Bonini and Attilio Loris Boner and Louis Philippe Boulet and Christopher Brightling and Jan L. Brożek and Andrew Bush and William W. Busse and Paulo Camargos and Giorgio Walter Canonica and Wendy Carr and Alfredo Cesario and Yu Zhi Chen and A M Chiriac and David J Costa and Linda Cox and Adnan Custovic and Rasmus Dahl and Ulf Darsow and T Didi and William K. Dolen and H. Douagui and Ruta Dubakiene and A El-Meziane and Jo{\~a}o A Fonseca and Wystke J Fokkens and Eleni Fthenou and Amiran Gamkrelidze and Judith Garcia-Aymerich and Roy Gerth van Wijk and Elena Gimeno-Santos and S. Guerra and Tari Haahtela and Hanna Haddad and Peter W Hellings and B. Hellquist-Dahl and Carsten Hohmann and P A Howarth and Jonathan O’B Hourihane and Michel Humbert and B{\'e}n{\'e}dicte Jacquemin and J. Just and O Kalayci and Michael A. Kaliner and Francine Kauffmann and M Kerkhof and Georges Khayat and B Koffi N'goran and Manolis Kogevinas and Gerard H Koppelman and Marek L Kowalski and Inger Kull and Piotr Kuna and D{\'e}sir{\'e}e Larenas and Iris Lavi and Lan Tt Le and Phillip Lieberman and Brian J Lipworth and Bassam H Mahboub and M. J. Makela and Faith Martin and Fernando D. Martinez and Gailen D. Marshall and {\'A}ngel Maz{\'o}n and Eric Mel{\'e}n and Eli O Meltzer and Florin Mihălţan and Yaser Mohammad and Alieh Mohammadi and Isabelle Momas and M{\'a}rio A Morais-Almeida and Joaquim Mullol and Antonella Muraro and Robert M. Naclerio and Salim Nafti and Leyla Seymurovna Namazova-Baranova and Martijn C. Nawijn and Tshipukane Dieudonn{\'e} Nyembue and Sam Oddie and Robin O'Hehir and Yoshitaka Okamoto and Maria Pia Orru and Cueneyt Ozdemir and Ganda St{\'e}phane Ouedraogo and Susanna Palkonen and Petr Panzner and Giovanni Passalacqua and Ruby Pawankar and Bernard Pigearias and Isabelle Pin and Mariona Pinart and Christophe M Pison and Ted A Popov and Della Porta and Dirkje S Postma and Denise Price and Klaus Friedrich Rabe and Julia Ratomaharo and Sakari Reitamo and D Rezagui and J. Ring and Rosemary Roberts and Joseph Roca and Britny Rogala and Antonino Romano and Jos{\'e} E Rosado-Pinto and Debbie Ryan and Mario S{\'a}nchez-Borges and Glenis Kathleen Scadding and Aadam Sheikh and F. Estelle R. Simons and Val{\'e}rie Siroux and PD Dr. P. Schmid-Grendelmeier and Henriette A Smit and Talantbek Sooronbaev and Renato T. Stein and Peter J. Sterk and Jordi Sunyer and Ingrid Terreehorst and Elina M Toskala and Yann Tremblay and Rudolf Valenta and Dominique Valeyre and O Vandenplas and Christiaan van Weel and Marina Vassilaki and Raphaelle Varraso and Giovanni Viegi and De-yun Wang and Magnus Wickman and D Williams and Stefan W{\"o}hrl and Julie Wright and Arzu Yorgancioglu and Osman Mohammed Yusuf and Heather Jessica Zar and Mario Emilio Zernotti and Mihaela Zidarn and Nongping Zhong and Torsten Zuberbier},
  journal={International archives of allergy and immunology},
  year={2012},
  volume={158 3},
  pages={216-31}
}
Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to… CONTINUE READING

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Assessment of problematic severe asthma in children

KC Lodrup Carlsen, G Hedlin, +3 authors JC De Jongste
Eur Respir J. 2011 Feb;37(2):432-40 • 2011
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