Severe cholestatic liver failure associated with gemcitabine adjuvant monotherapy for pancreatic cancer.

Abstract

We report a case of severe hepatic failure caused by gemcitabine hydrochloride (GEM) monotherapy after pancreaticoduodenectomy for advanced pancreatic cancer. A 73-year-old woman received GEM as an adjuvant chemotherapy. She suffered from progressive edema, fatigue, and jaundice after the third GEM administration. Severe liver dysfunction and elevation of… (More)
DOI: 10.1007/s12328-011-0257-2

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