Severe cell fragmentation in the endothelial cell apoptosis induced by snake apoptosis toxin VAP1 is an apoptotic characteristic controlled by caspases.

@article{Maruyama2005SevereCF,
  title={Severe cell fragmentation in the endothelial cell apoptosis induced by snake apoptosis toxin VAP1 is an apoptotic characteristic controlled by caspases.},
  author={Jiro Maruyama and Hiroshi Hayashi and Jun-ying Miao and Hitoshi Sawada and Satohiko Araki},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={2005},
  volume={46 1},
  pages={1-6}
}
Hemorrhagic snake venom induces apoptosis in vascular endothelial cells (VEC). Vascular apoptosis-inducing protein 1 (VAP1), which is identified as an apoptosis toxin against vascular endothelial cells, induces apoptosis accompanied by severe cell fragmentation compared with that of apoptosis due to other inducers. The mechanism of this morphologic feature… CONTINUE READING