Severe cardiopulmonary complications consistent with systemic inflammatory response syndrome caused by leukemia cell lysis in childhood acute myelomonocytic or monocytic leukemia.

@article{Hijiya2005SevereCC,
  title={Severe cardiopulmonary complications consistent with systemic inflammatory response syndrome caused by leukemia cell lysis in childhood acute myelomonocytic or monocytic leukemia.},
  author={Nobuko Hijiya and Monika L. Metzger and Stan Pounds and Jeffrey E Schmidt and Bassem I. Razzouk and Jeffrey E. Rubnitz and Scott C. Howard and C. Andi{\'o}n N{\'u}{\~n}ez and Ching-Hon Pui and Raul C. Ribeiro},
  journal={Pediatric blood & cancer},
  year={2005},
  volume={44 1},
  pages={63-9}
}
BACKGROUND Life-threatening pulmonary complications that coincide with cell lysis during early chemotherapy and that mimic systemic inflammatory response syndrome (SIRS) have been reported in patients with acute myeloid leukemia (AML). METHODS We reviewed the records of patients with de novo AML, excluding M3 and Down syndrome, treated at our institution between 1991 and 2002 to determine the prevalence of severe SIRS with grade 3/4 pulmonary complications and to identify AML subtypes… CONTINUE READING

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The Tumor Lysis Syndrome.

The New England journal of medicine • 2018

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