Severe autoimmune protein S deficiency in a boy with idiopathic purpura fulminans.

@article{Bergmann1995SevereAP,
  title={Severe autoimmune protein S deficiency in a boy with idiopathic purpura fulminans.},
  author={Frauke Bergmann and Peter Friedrich Hoyer and S. Vigano' D'Angelo and Giuseppina Mazzola and C Oestereich and Monika Barthels and Armando D'angelo},
  journal={British journal of haematology},
  year={1995},
  volume={89 3},
  pages={610-4}
}
Idiopathic purpura fulminans usually occurs in young children and is frequently preceded by a preparatory viral or bacterial infection. Following a severe streptococcal pharyngitis, an 8-year-old boy developed purpura fulminans with disseminated intravascular coagulation and severe protein S deficiency (total antigen < 0.05 u/ml). Despite generous plasma… CONTINUE READING