Severe aplastic anemia preceding acute lymphoblastic leukemia.

@article{Matloub1993SevereAA,
  title={Severe aplastic anemia preceding acute lymphoblastic leukemia.},
  author={Yousif H Matloub and Richard D. Brunning and Diane C. Arthur and Norma K. C. Ramsay},
  journal={Cancer},
  year={1993},
  volume={71 1},
  pages={264-8}
}
BACKGROUND Bone marrow aplasia preceding acute lymphoblastic leukemia (ALL) is a rare condition that usually affects children. The ALL generally follows the recovery of normal blood counts and most commonly occurs within 6 months of the onset of aplasia. The case of a patient with severe aplastic anemia is reported in whom ALL developed 15 months after the initial diagnosis of aplastic anemia. A literature search found 23 cases of ALL after a period of aplasia or hypoplasia. This patient's… CONTINUE READING
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