Severe amnesia following bilateral medial temporal lobe damage occurring on two distinct occasions

@article{Gennaro2006SevereAF,
  title={Severe amnesia following bilateral medial temporal lobe damage occurring on two distinct occasions},
  author={Giancarlo Di Gennaro and Liliana G. Grammaldo and Pier Paolo Quarato and Vincenzo Esposito and Addolorata Mascia and Anthony Michael Sparano and Giulio Nicol{\`o} Meldolesi and Angelo Picardi},
  journal={Neurological Sciences},
  year={2006},
  volume={27},
  pages={129-133}
}
A comprehensive neuropsychological assessment was performed on a 38-year-old woman with drug-resistant right temporal lobe epilepsy before temporal lobectomy, during a 2-year follow-up period, and approximately 3 years after surgery when she developed a malignant glioma in the left medial temporal lobe (MTL). Both before and after epilepsy surgery, memory function was normal. When the tumour was discovered, the patient suffered from severe retrograde and anterograde amnesia, whereas working… 
View on Springer
ncbi.nlm.nih.gov
27 Citations
Background Citations
9

27 Citations

Citation Type

Citation Type

Temporal Lobectomy with Delayed Amnesia Following a New Lesion on the Other Side
TLDR
Continuing or late recurrence of seizures from the remaining temporal lobe after temporal lobectomy can result in incapacitating amnesia if status epilepticus occurs, and other new lesions on the opposite side to surgery can have the same effect.
Possible autoantibody-negative limbic encephalitis after anterior temporal lobectomy for hippocampal sclerosis
TLDR
The case of a young man who underwent anterior left temporal lobectomy for a medically refractory temporal lobe epilepsy with an excellent seizure and neuropsychological outcome might contribute to shed light on the issue of the possible contralateral reorganization of memory processes subserved by the mesial temporal lobe structures chronically involved in epileptogenesis.
Selective anterograde amnesia with thalamus and hippocampal lesions in neuro-Behcet's disease
Preoperative of Verbal Episodic Memory Outcome Using fMRI
TLDR
One potential application of fMRI is to provide evidence about seizure focus laterality by measuring asymmetry of activation in the MTL, which might be useful for predicting seizure outcome after anterior temporal lobe (ATL) surgery.
Functional MRI is a valid noninvasive alternative to Wada testing
  • J. Binder
  • Medicine, Biology
    Epilepsy & Behavior
  • 2011
Preoperative prediction of verbal episodic memory outcome using FMRI.
  • J. Binder
  • Psychology
    Neurosurgery clinics of North America
  • 2011
Reliability of visual assessment of medial temporal lobe atrophy
TLDR
Investigation of the reliability of vaMTA using the Scheltens rating scale found that it can predict conversion from MCI to AD with similar accuracy as can volumetric calculations and multivariate analysis, and can be used as supportive biomarker in the work-up of AD.
Use of preoperative functional MRI to predict verbal memory decline after temporal lobe epilepsy surgery
TLDR
Whether preoperative language mapping using functional magnetic resonance imaging (fMRI) is useful for predicting which patients are likely to experience verbal memory decline after L‐ATL is investigated.
Use of fMRI Language Lateralization for Quantitative Prediction of Naming and Verbal Memory Outcome in Left Temporal Lobe Epilepsy Surgery
TLDR
Though the first priority in treating intractable epilepsy is seizure control, the importance of cognitive side effects for some patients undergoing left AT L surgery should not be underestimated or denied.
Could patients benefit from whole-brain radiotherapy with unilateral hippocampus sparing?
TLDR
This data indicates that conventional and innovative approaches to OncolOGY and RADIOTHERAPY should be considered as separate treatments for central giant cell granuloma.
...
1
2
3
...

References

SHOWING 1-10 OF 11 REFERENCES
Lateralizing value of memory tests in drug‐resistant temporal lobe epilepsy
TLDR
It is suggested that a non‐invasive, relatively short and unexpensive neuropsychological battery based on memory tests may profitably complement other well‐established diagnostic procedures such as video‐EEG or magnetic resonance imaging (MRI), at least in patients with drug‐resistant TLE due to hippocampal sclerosis.
Unilateral Amnesic Stroke: Six New Cases and a Review of the Literature
TLDR
Three distinct syndromes of unilateral amnesic stroke involving the territories of the posterior cerebral, anterior choroidal, and thalamic penetrating arteries are delineated.
Amnesia following traumatic bilateral fornix transection
TLDR
A patient who suffered a traumatic penetrating head injury that resulted in a significant and persistent anterograde amnesia is reported, providing evidence supporting the role of isolated fornix lesions in amnesia.
Neuropsychological aspects of epilepsy surgery
Interaction of cognitive aging and memory deficits related to epilepsy surgery
TLDR
The data confirm that age regression of verbal memory in left temporal lobe epilepsy is similar to that in healthy controls and suggest that memory prognosis in older age should be considered if more extensive temporal resections would be inevitable.
Temporal lobe epilepsy surgery: different surgical strategies after a non-invasive diagnostic protocol
TLDR
It is suggested that different TLE subsyndromes can be identified accurately using non-invasive anatomo–electro–clinical data and can be treated effectively and safely with tailored surgery.
Episodic memory, amnesia, and the hippocampal–anterior thalamic axis
TLDR
By utilizing new information from both clinical and experimental studies with animals, the anatomy underlying anterograde amnesia has been reformulated and places critical importance on the efferents from the hippocampus via the fornix to the diencephalon.
Hippocampal Amnesia
TLDR
Findings across cases include the association of bilateral hippocampal damage with a deficit in anterograde episodic memory combined with spared procedural and working memory and the limited nature of retrograde amnesia following lesions to the fornix.
Memory Lateralization in Medial Temporal Lobe Epilepsy Assessed by Functional MRI
Summary:  Purpose: To determine the utility of functional magnetic resonance imaging (fMRI) in preoperative lateralization of memory function in patients with medial temporal lobe epilepsy (MTLE).
Unilateral amnesic
  • stroke
  • 1993
...
1
2
...