Severe allergic hair dye reactions in 8 children

@article{Ssted2006SevereAH,
  title={Severe allergic hair dye reactions in 8 children},
  author={Heidi S{\o}sted and Jeanne Duus Johansen and Klaus Ejner Andersen and Torkil Menn{\'e}},
  journal={Contact Dermatitis},
  year={2006},
  volume={54}
}
Serious adverse skin reactions to permanent hair dyes and temporary black tattoos have been reported. As temporary tattoos have become fashionable among adolescents, the risk profile for p‐phenylenediamine (PPD) sensitization of the population has changed simultaneously with an increasing use of hair dyes in this age group. This investigation reports PPD sensitization in children with regard to cause of sensitization, clinical presentation and consequences. Clinical history and patch test… 
p-Phenylenediamine and Risk of Sensitization in Children
TLDR
It is not recommended to get temporary henna tattoos under any circumstances and children under the age of 16 years should not use permanent hair dyes in order to avoid severe allergic reactions and life-long sensitization to PPD.
Severe allergic hair dye reactions in 8 children
TLDR
The most important outcome of this study should be the need to identify strategies to expunge this a deliberate transepidermal violation of children with recognized allergens.
Contact dermatitis from a presumed allergy to paraphenylenediamine
TLDR
A case involving a patient who acquired a temporary tattoo while vacationing in Mexico and subsequently developed contact dermatitis at the tattoo site is presented.
Cosmetovigilance:the study of prevalence & vigilance of adverse cutaneous reactions in hairdye users
TLDR
The experience regarding the notification of adverse effects of cosmetics, although limited to a restricted geographical area, suggests that for an efficient and reliable monitoring system to be in place.
Henna tattoo contact dermatitis — a report of four cases and brief review of the selected literature
TLDR
The agent responsible for contact allergy was proven to be PPD in 3 patients, and in one patch testing revealed positive reactions to PPD and benzocaine, as well as to wool alcohols, nickel sulphate and potassium dichromate, to previously used hair dye—all being of clinical relevance.
Severe allergic reactions to para‐phenylenediamine in children and adolescents: should the patch test concentration of PPD be changed?
TLDR
This study has shown that henna tattoos containing para‐phenylenediamine (PPD) are a well‐known cause of severe contact dermatitis, mainly in children, and that hair dyes are a relevant exposure source to PPD.
Analysis of the Results from the Patch Test to Para-Phenylenediamine in the TRUE Test in Patients with a Hair Dye Contact Allergy
TLDR
Findings show that PPD is an effective HDCA marker, however, it is proposed that investigations on hair dye components other than PPD should be conducted to develop and validate additional predictive HDCA markers.
Allergic contact dermatitis in children: which factors are relevant? (review of the literature)
TLDR
The purpose of this review is to alert the paediatrician and dermatologist of the frequency of ACD in young children and of the importance of performing patch tests in every case of chronic recurrent or therapy‐resistant eczema in children.
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References

SHOWING 1-10 OF 27 REFERENCES
55 cases of allergic reactions to hair dye: a descriptive, consumer complaint‐based study
TLDR
PPD and its derivatives in hair dye at the present concentrations presents a significant health risk for the population and the severe acute allergic skin reactions are often misdiagnosed in the health care system.
Hair dye contact allergy: quantitative exposure assessment of selected products and clinical cases
TLDR
The aim of the present study was to identify dye precursors and couplers in hair dyeing products causing clinical hair dye dermatitis and to compare the data with the contents of these compounds in a randomly selected set of similar products.
Hair dye‐sensitized hairdressers: the cross‐reaction pattern with new generation hair dyes
TLDR
The data from this study suggest that for hairdressers sensitized to PPD and/ or DTS and/or ONPPD this new generation of hair dyes is a safe alternative for use in their salons.
Sensitization to Para‐Phenylenediamine from a Streetside Temporary Tattoo
TLDR
“Temporary” henna tattoos (skin painting or pseudotattooing) are in vogue among American and European youngsters, particularly when vacationing, but this short‐lived fad can have longer‐term sequelae then expected, ranging from postinflammatory hyperpigmentation of the tattoo site to permanent sensitization to PPD and related compounds.
Adverse reactions to cosmetics.
TLDR
It was found that hair dyes, lipsticks and surprisingly shaving creams caused more reaction as compared to other cosmetics, and labeling of the cosmetics should be done to help the dermatologists and the patients to identify the causative allergen in cosmetic preparation.
Sensitivity and specificity of the consumer open skin allergy test as a method of prediction of contact dermatitis to hair dyes.
TLDR
The results confirm the excellent predictive value of the SAT over the entire range of PPD concentrations used in oxidative hair colouring products and suggest that the test is a suitable tool for the secondary prevention of contact allergic reactions to hair Colouring products.
Contact dermatitis from paraphenylenediamine used as a skin paint
TLDR
A 32-year-old Somali Moslem woman developed an acute blistering eruption on the dorsum of her hands, forearms and feet 2 weeks after a friend had applied a PPD-containing black hair dye (BigenA) as a decorative skin paint.
High frequency of simultaneous sensitivity to Disperse Orange 3 in patients with positive patch tests to para‐phenylenediamine
TLDR
The frequency of simultaneous patch test reactions to PPD and DO3 is interpreted as due either to cross‐sensitivity proper, or to metabolic conversion of textile dyes in the skin to P PD.
Ranking of hair dye substances according to predicted sensitization potency: quantitative structure–activity relationships
TLDR
All hair dye substances registered in Europe and to provide their tonnage data were identified and the sensitization potential of each substance was estimated by using a quantitative structure–activity relationship (QSAR) model and the substances were ranked according to their predicted potency.
Identification and quantification of para-phenylenediamine in a temporary black henna tattoo.
TLDR
The presence of PPD in black henna tattoo mixtures in high concentration poses a health hazard and a risk of allergic contact sensitization with potential long-term consequences.
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