Severe affective and behavioral dysregulation in youths is associated with a proinflammatory state.

@article{Holtmann2013SevereAA,
  title={Severe affective and behavioral dysregulation in youths is associated with a proinflammatory state.},
  author={Martin Holtmann and Luise Poustka and Florian Daniel Zepf and Tobias Banaschewski and Josef Priller and Sven B{\"o}lte and Tanja Legenbauer},
  journal={Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie},
  year={2013},
  volume={41 6},
  pages={393-9}
}
OBJECTIVE A heritable behavioral phenotype, the so-called Dysregulation Profile (DP), characterized by extreme scores on the syndrome scales Anxious/Depressed (A/D), Attention Problems (AP), and Aggressive Behavior (AGG), has been identified on the Child Behavior Checklist (CBCL). It characterizes children with severe affective and behavioral dysregulation. The present study examined possible alterations of the inflammatory system in CBCL-DP using a clinical sample of n = 133 children and… CONTINUE READING