Severe adverse drug reactions.

  title={Severe adverse drug reactions.},
  author={Y Teo and Sarah Walsh},
  journal={Clinical medicine},
  volume={16 1},
Severe cutaneous adverse reactions (SCARs) can present in a multitude of ways including Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, and acute generalised exanthematous pustulosis. While the prognosis and therapy for these conditions may vary, it is crucial that the culprit drug is identified and withheld early as this can influence patient outcome. Mainstay of management is by supportive therapy. In all SCARs, long-term sequelae… CONTINUE READING