Severe Obstructive Sleep Apnea Is Associated with Higher Brain Amyloid Burden: A Preliminary PET Imaging Study.

@article{Jackson2020SevereOS,
  title={Severe Obstructive Sleep Apnea Is Associated with Higher Brain Amyloid Burden: A Preliminary PET Imaging Study.},
  author={Melinda L. Jackson and Marina G. Cavuoto and Rachel Schembri and Vincent Dor{\'e} and Victor L. Villemagne and Maree Barnes and Fergal J O'Donoghue and Christopher C. Rowe and Stephen R. Robinson},
  journal={Journal of Alzheimer's disease : JAD},
  year={2020}
}
BACKGROUND Obstructive sleep apnea (OSA) has been linked to an increase risk of dementia. Few studies have cross-sectionally examined whether clinically-confirmed OSA is associated with a higher brain amyloid burden. OBJECTIVE The aim of this study was to compare brain amyloid burden in individuals with untreated OSA and healthy controls, and explore associations between amyloid burden and polysomnographic and subjective measures of sleep, demographics, and mood. METHODS Thirty-four… Expand
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