Severe Acute Respiratory Syndrome in Association with Human Leukocyte Antigen and Clinical Implications

@inproceedings{Cheepsattayakorn2017SevereAR,
  title={Severe Acute Respiratory Syndrome in Association with Human Leukocyte Antigen and Clinical Implications},
  author={Attapon Cheepsattayakorn},
  year={2017}
}
Human leukocyte antigen (HLA) is the most polymorphic genetic system in humans, with numerous alleles, and subsequently, various possible combinations [1]. These genes, the products of histocompatibility complex (MHC) [2] are located in the short arm of chromosome 6 at band p 21.3 [2] and are divided into three classes, I, II and III [1]. HLA class I is responsible for coding the molecules HLA-A, -B and -C, present in almost all somatic cells with killing of viral infected targets by class I… CONTINUE READING