Severe ADC decreases do not predict irreversible tissue damage in humans.

@article{Fiehler2002SevereAD,
  title={Severe ADC decreases do not predict irreversible tissue damage in humans.},
  author={Jens Fiehler and Mascha Foth and Thomas Kucinski and Ren{\'e}e Knab and Michael von Bezold and Cornelius Weiller and Hermann Zeumer and Joachim Roether},
  journal={Stroke},
  year={2002},
  volume={33 1},
  pages={79-86}
}
BACKGROUND AND PURPOSE A mismatch between diffusion- and perfusion-weighted MRI is thought to define tissue at risk of infarction. This concept is based on the assumption that diffusion slowing of and decreases in the apparent diffusion coefficient (ADC) serve as indicator of tissue proceeding to infarction. We tested this hypothesis. METHODS MRI (diffusion weighted, perfusion weighted, MRA, T2 weighted) was performed in 15 patients with acute stroke within 2.9+/-0.8 hours (mean+/-SD) of… CONTINUE READING