Severe, rapidly progressive human immunodeficiency virus type 1 disease in newborns with coinfections.

@article{Pillay2001SevereRP,
  title={Severe, rapidly progressive human immunodeficiency virus type 1 disease in newborns with coinfections.},
  author={Tanyia Pillay and Miriam Adhikari and John Mokili and Dhayendre Moodley and C Connolly and T. Doorasamy and Hoosen Mahomed Coovadia},
  journal={The Pediatric infectious disease journal},
  year={2001},
  volume={20 4},
  pages={404-10}
}
AIM To describe a severe form of rapidly progressive HIV-1 infection manifesting in the neonatal period. METHOD Prospective cohort study, King Edward VIII Hospital, Durban, South Africa. HIV-1-exposed neonates with hepatosplenomegaly, lymphadenopathy or persistent pneumonia within the first 28 days of life were investigated for perinatal infections. Confirmation of neonatal HIV-1 infection, HIV-1 subtype and clinical outcomes were studied. RESULTS Twenty-three (72%) of 32 symptomatic HIV-1… CONTINUE READING

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