Several new isoprenoids from the soft coral sinularia erecta

  title={Several new isoprenoids from the soft coral sinularia erecta},
  author={Rudi and T Lev-AriDayan and Aknin and Gaydou and Kashman},
  journal={Journal of natural products},
  volume={61 7},
Eight compounds were isolated from the Indo-Pacific soft coral Sinularia erecta (Tixier-Durivault, 1945) collected from the lagoon of Mayotte, Comoros Islands, northwest of Madagascar. Four of the compounds, namely the sesquiterpene germacrene D, the diterpenoids nephthenol and decaryiol, and norcembrene, are known. The other four are the new secondary metabolites germacrene E (1), epi-norcembrene (3), and two bis-pukalide diterpenes, mayotolides A and B (4 and 5). The structure of each of the… 
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Several of the previously published secondary metabolites of the soft coral genus Sinularia are reexamined for their pharmacological properties, and the results strongly support further investigations.
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Biogenesis, suggested biosynthesis, based on the structure and mainly known terrestrial biosynthesis is proposed for diterpenoids and higher isoprenoids.
Bioactive norditerpenoids from the soft coral Sinularia gyrosa.