Several mediators appear to interact in neurogenic inflammation.

  title={Several mediators appear to interact in neurogenic inflammation.},
  author={Rainer Gamse and Martin Posch and Alois Saria and G{\'a}bor Jancs{\'o}},
  journal={Acta physiologica Hungarica},
  volume={69 3-4},
Plasma protein extravasation was studied in the rat abdominal skin. Substance P (SP), neurokinin A (NKA) and B (NKB) were found to induce extravasation with a threshold dose of about 1 pmol. Calcitonin gene-related peptide (CGRP) caused no or little extravasation alone but it potentiated the action of SP, NKA, NKB, and physalaemin. The potentiation of the… CONTINUE READING