Several mRNAs with variable 3' untranslated regions and different stability encode the human PR264/SC35 splicing factor.

@article{Sureau1994SeveralMW,
  title={Several mRNAs with variable 3' untranslated regions and different stability encode the human PR264/SC35 splicing factor.},
  author={Alain Sureau and Bernard V. Perbal},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1994},
  volume={91 3},
  pages={
          932-6
        }
}
We have recently established that several mRNAs encode the PR264/SC35 splicing factor and that their expression is related to that of c-Myb in human hematopoietic cells. We now report that the various PR264 mRNAs whose expression is transactivated by c-Myb proteins encode an identical PR264/SC35 polypeptide. These mRNAs differ only in their 3' untranslated sequences and exhibit significantly different half-lives. We also show that there is a direct correlation between the length of the 3… CONTINUE READING
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