Several interleukin-4 and interleukin-13 gene single nucleotide polymorphisms among Chinese asthmatic patients.

@article{Jiang2009SeveralIA,
  title={Several interleukin-4 and interleukin-13 gene single nucleotide polymorphisms among Chinese asthmatic patients.},
  author={Peng Jiang and Ji Liu and Xue-Bo Yan and Rong-yu Liu},
  journal={Allergy and asthma proceedings},
  year={2009},
  volume={30 4},
  pages={413-8}
}
Asthma is a common respiratory disease associated with airway hyperactivity and high total serum immunoglobulin E (IgE) levels. The asthmatic phenotypes are widely considered to be caused by environmental effects on genetically predisposed individuals. Interleukin (IL)-4 and IL-13 act on B cells and regulate the IgE production, and the single nucleotide polymorphisms (SNPs) in the IL-4 and IL-13 genes are implicated in the pathogenesis of asthma. To study the association of IL-4 and IL-13 gene… CONTINUE READING