Seventy-five years of Resochin® in the fight against malaria

@article{Jensen2009SeventyfiveYO,
  title={Seventy-five years of Resochin® in the fight against malaria},
  author={M. Jensen and H. Mehlhorn},
  journal={Parasitology Research},
  year={2009},
  volume={105},
  pages={609-627}
}
  • M. Jensen, H. Mehlhorn
  • Published 2009
  • Biology, Medicine
  • Parasitology Research
  • The four different forms of human malaria have threatened humanity since time immemorial and to this day, they exact a death toll of one to three million people annually. Synthetic anti-malarial agents have been in development since early 1900. Perhaps the most successful and widely used drug, Resochin® (chloroquine), was discovered 75 years ago; for a long time, it was the drug of choice and to this day, it is still used in many regions of the world as a reliable treatment against simpler… CONTINUE READING
    87 Citations

    Figures, Tables, and Topics from this paper

    Introducing New Antimalarial Analogues of Chloroquine and Amodiaquine: A Narrative Review
    • 40
    • Highly Influenced
    Malaria drug resistance: new observations and developments.
    • 45
    • PDF
    Drug resistance in Plasmodium
    • 121
    Molecular basis for the mechanism of action and resistance to artemisinin combination therapy in Plasmodium falciparum
    • Pedro Ferreira
    • Biology
    • 2010
    Artemisinin resistance: current status and scenarios for containment
    • 196
    Postrenal transplant Plasmodium vivax malaria: neglected and not benign
    • 10

    References

    SHOWING 1-10 OF 47 REFERENCES
    Chloroquine-resistant malaria.
    • 438
    • PDF
    Malaria: progress, perils, and prospects for eradication.
    • 669
    • PDF
    Evidence of artemisinin-resistant malaria in western Cambodia.
    • 1,388
    History, Dynamics, and Public Health Importance of Malaria Parasite Resistance
    • 301
    • PDF
    Qinghaosu (artemisinin): an antimalarial drug from China
    • 1,531
    • PDF
    Pitfalls in a discovery: the chronicle of chloroquine.
    • G. R. Coatney
    • Medicine
    • The American journal of tropical medicine and hygiene
    • 1963
    • 116
    • Highly Influential
    • PDF
    Comparative genomics of the neglected human malaria parasite Plasmodium vivax
    • 714
    • PDF
    Impact of chloroquine resistance on malaria mortality.
    • 461