Seven novel KIT mutations in horses with white coat colour phenotypes.

  title={Seven novel KIT mutations in horses with white coat colour phenotypes.},
  author={Bianca Haase and S A Brooks and Teruaki Tozaki and Dominik Burger and P-A Poncet and Stefan Rieder and Telhisa Hasegawa and Cecilia T. Penedo and Tosso Leeb},
  journal={Animal genetics},
  volume={40 5},
White coat colour in horses is inherited as a monogenic autosomal dominant trait showing a variable expression of coat depigmentation. Mutations in the KIT gene have previously been shown to cause white coat colour phenotypes in pigs, mice and humans. We recently also demonstrated that four independent mutations in the equine KIT gene are responsible for the dominant white coat colour phenotype in various horse breeds. We have now analysed additional horse families segregating for white coat… CONTINUE READING
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