Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: a HuGE association review and meta-analysis.

@article{Sagoo2008SevenLL,
  title={Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: a HuGE association review and meta-analysis.},
  author={Gurdeep S. Sagoo and Iain D Tatt and Georgia Salanti and Adam S. Butterworth and Nadeem Sarwar and Merel C. van Maarle and J Wouter Jukema and Bj{\"o}rn Wiman and John J. P. Kastelein and Anna Michaela Bennet and Ulf H de Faire and John Danesh and Julian P. T. Higgins},
  journal={American journal of epidemiology},
  year={2008},
  volume={168 11},
  pages={
          1233-46
        }
}
Lipoprotein lipase (LPL) is a key enzyme in lipoprotein metabolism and a major candidate gene for coronary heart disease (CHD). The authors assessed associations between 7 LPL polymorphisms and lipid fractions and CHD risk in population-based cohort, case-control, and cross-sectional studies published by January 2007. Meta-analyses of 22,734 CHD cases and 50,177 controls in 89 association studies focused on the relations of the T-93G (rs1800590), D9N (rs1801177), G188E, N291S (rs268), PvuII… CONTINUE READING

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Effect of the Asp9 to Asn polymorphism in lipoprotein lipase on plasma

  • G Eiriksdottir, O Bergmann, MK Bolla
  • Sagoo et al. Am J Epidemiol
  • 2008

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