Seven genomic subtypes of chronic fatigue syndrome/myalgic encephalomyelitis: a detailed analysis of gene networks and clinical phenotypes

@article{Kerr2007SevenGS,
  title={Seven genomic subtypes of chronic fatigue syndrome/myalgic encephalomyelitis: a detailed analysis of gene networks and clinical phenotypes},
  author={Jonathan R Kerr and Beverley Burke and Robert D. Petty and John Gough and David J. Fear and Derek L. Mattey and John S. Axford and Angus George Dalgleish and David J. Nutt},
  journal={Journal of Clinical Pathology},
  year={2007},
  volume={61},
  pages={730 - 739}
}
  • J. Kerr, B. Burke, D. Nutt
  • Published 5 December 2007
  • Biology, Medicine, Psychology
  • Journal of Clinical Pathology
Aim: Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a multisystem disease, the pathogenesis of which remains undetermined. The authors have recently reported a study of gene expression that identified differential expression of 88 human genes in patients with CFS/ME. Clustering of quantitative PCR (qPCR) data from patients with CFS/ME revealed seven distinct subtypes with distinct differences in Medical Outcomes Survey Short Form-36 scores, clinical phenotypes and severity… 

Gene profiling of patients with chronic fatigue syndrome/myalgic encephalomyelitis

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  • 2008
Seven subtypes of Chronic fatigue syndrome/myalgic encephalomyelitis are revealed with distinct differences in Short Form (SF)-36 scores, clinical phenotypes, and severity; the possibility that these subtypes represent individual host responses to particular microbial infections is being investigated.

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Pathological Mechanisms Underlying Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

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Latent class analysis of a heterogeneous international sample of patients with myalgic encephalomyelitis/chronic fatigue syndrome

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...

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