Seven-Year Efficacy of RTS,S/AS01 Malaria Vaccine among Young African Children.

@article{Olotu2016SevenYearEO,
  title={Seven-Year Efficacy of RTS,S/AS01 Malaria Vaccine among Young African Children.},
  author={Ally Ibrahim Olotu and Gregory Fegan and Juliana Wambua and George M. Nyangweso and Amanda R. Leach and Marc J. J. Lievens and David C Kaslow and Patricia W Njuguna and Kevin Marsh and Philip Bejon},
  journal={The New England journal of medicine},
  year={2016},
  volume={374 26},
  pages={
          2519-29
        }
}
BACKGROUND The candidate malaria vaccine RTS,S/AS01 is being evaluated in order to inform a decision regarding its inclusion in routine vaccination schedules. METHODS We conducted 7 years of follow-up in children who had been randomly assigned, at 5 to 17 months of age, to receive three doses of either the RTS,S/AS01 vaccine or a rabies (control) vaccine. The end point was clinical malaria (temperature of ≥37.5°C and infection with Plasmodium falciparum of >2500 parasites per cubic millimeter… CONTINUE READING
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Ef - ficacy and safety of RTS , S / AS 01 malaria vaccine with or without a booster dose in infants and children in Africa : final results of a phase 3 , individually randomised , controlled trial

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Ef - ficacy and safety of the RTS , S / AS 01 malaria vaccine during 18 months after vaccination : a phase 3 randomized , controlled trial in children and young infants at 11 African sites

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