Setup of a bone aging experimental model in the rabbit comparing changes in cortical and trabecular bone: Morphological and morphometric study in the femur.

@article{Pazzaglia2015SetupOA,
  title={Setup of a bone aging experimental model in the rabbit comparing changes in cortical and trabecular bone: Morphological and morphometric study in the femur.},
  author={Ugo E Pazzaglia and Valeria Sibilia and Terenzio Congiu and Francesca Pagani and Marco Ravanelli and Guido Zarattini},
  journal={Journal of morphology},
  year={2015},
  volume={276 7},
  pages={733-47}
}
Bone aging was studied in an experimental model (rabbit femur) in three populations aged 0.5, 1.5, and 7.5 years. Cortical bone histology was compared with a data set from a 1.5-month-old population of an earlier published paper. From 0.5-year-old onward, the mean femur length did not increase further. Thereafter, the mean marrow area increased and the cortical area decreased significantly with aging. This was associated with a structural pattern transformation from plexiform to laminar and… CONTINUE READING
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