Setting the standard in T-cell-depleted haploidentical transplantation and beyond.

@article{Aversa2011SettingTS,
  title={Setting the standard in T-cell-depleted haploidentical transplantation and beyond.},
  author={Franco Aversa},
  journal={Best practice & research. Clinical haematology},
  year={2011},
  volume={24 3},
  pages={325-9}
}
Much progress has been made in the clinical, biological and technical aspects of the T-cell-depleted haploidentical hematopoietic stem cell transplantation (HSCT). Our experience demonstrates that infusing a megadose of extensively T-cell-depleted hematopoietic peripheral blood stem cells after an immuno-myeloablative conditioning regimen in acute leukemia patients ensures sustained engraftment with minimal GvHD without the need of any post-transplant immunosuppressive treatment. Since our… CONTINUE READING