Setting the stage for individualized therapy in hemophilia: What role can pharmacokinetics play?

Abstract

Replacement therapy with clotting factor concentrates (CFC) is the mainstay of treatment in hemophilia. Its widespread application has led to a dramatic decrease in morbidity and mortality in patients, with concomitant improvement of quality of life. However, dosing is challenging and costs are high. This review discusses benefits and limitations of… (More)
DOI: 10.1016/j.blre.2018.01.001

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