Setting the stage for development: mRNA translation and stability during oocyte maturation and egg activation in Drosophila.

@article{Tadros2005SettingTS,
  title={Setting the stage for development: mRNA translation and stability during oocyte maturation and egg activation in Drosophila.},
  author={Wael Tadros and Howard D. Lipshitz},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2005},
  volume={232 3},
  pages={593-608}
}
Early animal development is controlled by maternally encoded RNAs and proteins, which are loaded into the egg during oogenesis. Oocyte maturation and egg activation trigger changes in the translational status and the stability of specific maternal mRNAs. Whereas both maturation and activation have been studied in depth in amphibians and echinoderms, only recently have these processes begun to be dissected using the powerful genetic and molecular tools available in Drosophila. This review… CONTINUE READING
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