Set positive end-expiratory pressure during protective ventilation affects lung injury.

@article{Takeuchi2002SetPE,
  title={Set positive end-expiratory pressure during protective ventilation affects lung injury.},
  author={Muneyuki Takeuchi and Sven Goddon and Marisa Dolhnikoff and Motomu Shimaoka and Dean Hess and Marcelo Britto Passos Amato and Robert M. Kacmarek},
  journal={Anesthesiology},
  year={2002},
  volume={97 3},
  pages={682-92}
}
BACKGROUND The most appropriate method of determining positive end-expiratory pressure (PEEP) level during a lung protective ventilatory strategy has not been established. METHODS In a lavage-injured sheep acute respiratory distress syndrome model, the authors compared the effects of three approaches to determining PEEP level after a recruitment maneuver: (1) 2 cm H(2)O above the lower inflection point on the inflation pressure-volume curve, (2) at the point of maximum curvature on the… CONTINUE READING