Sesquiterpenoids from Inula lineariifolia inhibit nitric oxide production.

@article{Nie2010SesquiterpenoidsFI,
  title={Sesquiterpenoids from Inula lineariifolia inhibit nitric oxide production.},
  author={Li-Yue Nie and Jiang-jiang Qin and Ying Huang and Lan Ying Yan and Yu-Bo Liu and Yue-Xing Pan and Huizi Jin and Wei-dong Zhang},
  journal={Journal of natural products},
  year={2010},
  volume={73 6},
  pages={
          1117-20
        }
}
Fourteen sesquiterpenoids including six new analogues (1-6) were isolated from the aerial parts of Inula lineariifolia.. The structures of the new sesquiterpenoids were determined by spectroscopic data analysis, and the structures of 1 and 6 were confirmed by single-crystal X-ray diffraction data and the modified Mosher method. All 14 compounds were examined for the inhibition of LPS-induced nitric oxide production in RAW264.7 macrophages. Compounds 6, 13, and 14 were found to inhibit nitric… CONTINUE READING

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