Sesquiterpene lactones: adverse health effects and toxicity mechanisms.

  title={Sesquiterpene lactones: adverse health effects and toxicity mechanisms.},
  author={Marco Amorim and Rui M Gil da Costa and Carlos Frederico Costa Lopes and Margarida M. S. M. Bastos},
  journal={Critical reviews in toxicology},
  volume={43 7},
Sesquiterpene lactones (STLs) present a wide range of biological activities, mostly based on their alkylating capabilities, which underlie their therapeutic potential. These compounds are the active constituents of a variety of plants, frequently used as herbal remedies. STLs such as artemisinin and its derivatives are in use as first-line antimalarials while others, such as parthenolide, have recently reached cancer clinical trials. However, the toxicological profile of these compounds must be… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 27 extracted citations

Similar Papers

Loading similar papers…