Sesquiterpene lactone arglabin influences DNA synthesis in P388 leukemia cells in vivo


The antitumor activity of sesquiterpene lactones of the germacrane series was discovered in 1970s [1]. (10)-Epoxy-5,7(H),6,11 (H)-guai-3(4)-11(12)-dien-6(12)-olide (I, arglabin), representing sesquiterpene -lactones of the guaiane type 1, was originally isolated in 1980 from Artemisia glabella Kar. et Kir., an endemic wormwood species occurring in Central… (More)
DOI: 10.1007/s11094-005-0052-9


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