Sesquiterpene constituents from the soft coral Sinularia nanolobata

@article{Ngoc2017SesquiterpeneCF,
  title={Sesquiterpene constituents from the soft coral Sinularia nanolobata},
  author={Ninh Thi Ngoc and Pham Thi Thu Huong and Nguyen Van Thanh and Nguyen Xuan Cuong and Nguyen Hoai Nam and Do Cong Thung and Phan Van Kiem and Ch{\^a}u Văn Minh},
  journal={Natural Product Research},
  year={2017},
  volume={31},
  pages={1799 - 1804}
}
Abstract Using various chromatographic separations, four sesquiterpenes (1–4), including two new compounds, nanolobatols A and B (1 and 2), were isolated from the Vietnamese soft coral Sinularia nanolobata. Their structures were determined on the basis of spectroscopic data (1H and 13C NMR, HSQC, HMBC, 1H–1H COSY, NOESY and FT-ICR-MS) and by comparison with the literature values. The cytotoxic activity of isolated compounds against a panel of eight human cancer cell lines was also evaluated. 
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TLDR
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Four new sesquiterpenes, sinularianins C–F (3–6), together with known sinularianins A (1) and B (2) were identified from a South China Sea soft coral Sinularia sp. Compounds 1–6 were evaluated for…
Steroidal and α-tocopherylhydroquinone glycosides from two soft corals Cladiella hirsuta and Sinularia nanolobata
Two new pregnane glycosides, hirsutosterosides A and B (1 and 2), as well as two new α-tocopherylhydroquinone glycosides, cladophenol glycosides A and B (3 and 4) were isolated from a soft coral…
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TLDR
The cytotoxicity of 1−6 against the growth of a limited panel of cancer cell lines is described and the structures of 1+5 were elucidated on the basis of extensive spectroscopic analyses and by comparison of the spectral data with those of the related metabolites.
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TLDR
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TLDR
The structures of these metabolites were elucidated on the basis of extensive spectroscopic analysis and the anti-HCMV activity of 1–4 and its cytotoxicity against selected cell lines were evaluated.
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