Sesamin attenuates intercellular cell adhesion molecule-1 expression in vitro in TNF-alpha-treated human aortic endothelial cells and in vivo in apolipoprotein-E-deficient mice.

Abstract

Sesame lignans have antioxidative and anti-inflammatory properties. We focused on the effects of the lignans sesamin and sesamol on the expression of endothelial-leukocyte adhesion molecules in tumor necrosis factor-alpha (TNF-alpha)-treated human aortic endothelial cells (HAECs). When HAECs were pretreated with sesamin (10 or 100 microM), the TNF-alpha… (More)
DOI: 10.1002/mnfr.200900271

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@article{Wu2010SesaminAI, title={Sesamin attenuates intercellular cell adhesion molecule-1 expression in vitro in TNF-alpha-treated human aortic endothelial cells and in vivo in apolipoprotein-E-deficient mice.}, author={Wen-Huey Wu and Shu-Huei Wang and I H Kuan and Ya-Shi Kao and Pei-Jhen Wu and Chan-Jung Liang and Hsiung-Fei Chien and C Kao and Ching-Jang Huang and Yuh-Lien Chen}, journal={Molecular nutrition & food research}, year={2010}, volume={54 9}, pages={1340-50} }