Serum vasoconstrictor (serotonin) the presence of creatinine in the complex; a proposed structure of the vasoconstrictor principle.

@article{Rapport1949SerumV,
  title={Serum vasoconstrictor (serotonin) the presence of creatinine in the complex; a proposed structure of the vasoconstrictor principle.},
  author={Maurice M. Rapport},
  journal={The Journal of biological chemistry},
  year={1949},
  volume={180 3},
  pages={
          961-9
        }
}
In the fourth paper in this series (1) the isolation of the substance believed to be responsible for the marked vasoconstrictor activity of serum was reported. This substance was characterized as an indole derivative from its ultraviolet absorption spectrum and its behavior in various color and other chemical reactions. The analytical data agreed well with the empirical formula C14Hz103Nb.H2S04. The titration curve in aqueous solution revealed two titratable groups with PK’~ of 4.9 and pK’2 of… CONTINUE READING

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