Serum vascular endothelial growth factor-C and lymphoangiogenesis are associated with the lymph node metastasis and prognosis of patients with colorectal cancer.

@article{Wang2011SerumVE,
  title={Serum vascular endothelial growth factor-C and lymphoangiogenesis are associated with the lymph node metastasis and prognosis of patients with colorectal cancer.},
  author={Tian-bao Wang and Zhong-gang Chen and Xiu-qing Wei and Bo Wei and Wen-guang Dong},
  journal={ANZ journal of surgery},
  year={2011},
  volume={81 10},
  pages={694-9}
}
BACKGROUND The study aims to investigate the relationship among serum vascular endothelial growth factor (SVEGF-C), VEGF-C expression and lymph vessel density (LVD) in tumour tissue, and their influence to colorectal carcinoma (CRC). METHODS The SVEGF-C concentration of 110 patients with CRC and 40 healthy donors was examined by ELISA. The 110 tumour tissues and 40 normal colorectal specimens were examined by immunohistochemical staining (SP method) with VEGF-C and podoplanin (lymphatic… CONTINUE READING
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