Serum tryptase levels in patients with mastocytosis: correlation with mast cell burden and implication for defining the category of disease.

@article{Sperr2002SerumTL,
  title={Serum tryptase levels in patients with mastocytosis: correlation with mast cell burden and implication for defining the category of disease.},
  author={Wolfgang R Sperr and John-Hendrik Jordan and Michael Fiegl and L. M. Escribano and Carmen Bellas and Stephan R Dirnhofer and Hans Semper and Ingrid Simonitsch-Klupp and H P Horny and Peter Valent},
  journal={International archives of allergy and immunology},
  year={2002},
  volume={128 2},
  pages={136-41}
}
BACKGROUND The serum tryptase level is used as a diagnostic marker in mastocytosis and is considered to reflect the burden of (neoplastic) mast cells (MC). METHODS In the present study, serum tryptase levels were measured in patients with mastocytosis by fluoroenzyme immunoassay and compared with the extent of infiltration of the bone marrow (BM) by… CONTINUE READING