Serum tryptase concentration and progression to end-stage renal disease.

Abstract

BACKGROUND Mast cell activation can lead to nonclassical activation of the Renin-Angiotensin-Aldosterone System. However, the relevance of this to human chronic kidney disease is unknown. We assessed the association between serum tryptase, a product of mast cell activation, and progression to end-stage renal disease or mortality in patients with advanced… (More)
DOI: 10.1111/eci.12622

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