Serum total and high molecular weight adiponectin levels are correlated with the severity of diabetic retinopathy and nephropathy.

@article{Kato2008SerumTA,
  title={Serum total and high molecular weight adiponectin levels are correlated with the severity of diabetic retinopathy and nephropathy.},
  author={Kenichi Kato and Haruhiko Osawa and Masaaki Ochi and Yukiko Kusunoki and Osamu Ebisui and Keizo Ohno and Jun Ohashi and Ikki Shimizu and Y Fujii and Mitsune Tanimoto and Hideichi Makino},
  journal={Clinical endocrinology},
  year={2008},
  volume={68 3},
  pages={442-9}
}
OBJECTIVE Adiponectin is secreted specifically from adipocytes, and improves insulin sensitivity. Of its isoforms, the high molecular weight (HMW) complex is thought to be the most active. The aim of this study was to determine the relationship between serum total or HMW adiponectin and diabetic microangiopathy. DESIGN, PATIENTS AND MEASUREMENTS We analysed 198 Japanese patients with type 2 diabetes mellitus (T2DM) whose fasting serum samples were available. Serum total adiponectin and HMW… CONTINUE READING