Serum thymidine kinase activity in clinically healthy and diseased cats: a potential biomarker for lymphoma

  title={Serum thymidine kinase activity in clinically healthy and diseased cats: a potential biomarker for lymphoma},
  author={Samantha Taylor and Steve Dodkin and Kostas Papasouliotis and Helen Evans and Peter A Graham and Zoe Belshaw and Sara Westberg and Henrik P von Euler},
  journal={Journal of Feline Medicine and Surgery},
  pages={142 - 147}
The thymidine kinases are enzymes that convert deoxythymidine to deoxythymidine monophosphate and have a function in DNA synthesis. Rapidly proliferating cells will have higher levels of thymidine kinase. Serum thymidine kinase activity (sTK) is a useful tumour marker in humans and dogs, with utility as a prognostic indicator in lymphoma. In the current study serum samples were collected from 49 clinically healthy cats, 33 with lymphoma, 55 with inflammatory disease and 34 with non… 

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