Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD.

@article{Lomas2009SerumSP,
  title={Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD.},
  author={David A. Lomas and Edwin K. Silverman and Lisa D. Edwards and Nicholas W Locantore and Bruce E. Miller and Donald H. Horstman and Ruth Tal-Singer},
  journal={The European respiratory journal},
  year={2009},
  volume={34 1},
  pages={
          95-102
        }
}
Surfactant protein (SP)-D is a lung-derived protein that has been proposed as a biomarker for inflammatory lung disease. Serum SP-D was evaluated as a biomarker for components of chronic obstructive pulmonary disease (COPD) in the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) cohort and its response assessed to the administration of the anti-inflammatory agent prednisolone. The median level of serum SP-D was significantly elevated in 1,888 individuals… CONTINUE READING

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