Serum sex steroids in premenopausal women and breast cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC).

@article{Kaaks2005SerumSS,
  title={Serum sex steroids in premenopausal women and breast cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC).},
  author={Rudolf Kaaks and Franco Berrino and Timothy J Key and Sabina Rinaldi and Laure Dossus and Carine Biessy and Giorgio Secreto and Pilar Amiano and Sheila Anne Bingham and H. B{\"o}ing and H Bas Bueno de Mesquita and Jenny Chang-Claude and Francoise Clavel-Chapelon and Agn{\`e}s Fournier and Carla H van Gils and Carlos A. Gonz{\'a}lez and Aurelio Barricarte Gurrea and Elena Critselis and Kay T Khaw and Vittorio Krogh and Petra H. Lahmann and Gabriele Nagel and Anja Olsen and N. Charlotte Onland-Moret and Kim Overvad and Domenico Palli and Salvatore Panico and P. H. Peeters and Jos{\'e} Ram{\'o}n Quir{\'o}s and Andrew Wilfred Roddam and Anne C. M. Thi{\'e}baut and Anne Tj{\o}nneland and Ma Dolores Chirlaque and Antonia Trichopoulou and Dimitirios Trichopoulos and Rosario Tumino and Paolo Vineis and Teresa Norat and Pietro Ferrari and Nadia Slimani and Elio Riboli},
  journal={Journal of the National Cancer Institute},
  year={2005},
  volume={97 10},
  pages={
          755-65
        }
}
BACKGROUND Contrasting etiologic hypotheses about the role of endogenous sex steroids in breast cancer development among premenopausal women implicate ovarian androgen excess and progesterone deficiency, estrogen excess, estrogen and progesterone excess, and both an excess or lack of adrenal androgens (dehydroepiandrosterone [DHEA] or its sulfate [DHEAS]) as risk factors. We conducted a case-control study nested within the European Prospective Investigation into Cancer and Nutrition cohort to… CONTINUE READING
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