Serum sex hormone-binding globulin and serum nonsex hormone-binding globulin-bound testosterone fractions in prepubertal boys with chronic renal failure.

@article{Belgorosky1991SerumSH,
  title={Serum sex hormone-binding globulin and serum nonsex hormone-binding globulin-bound testosterone fractions in prepubertal boys with chronic renal failure.},
  author={Alicia Belgorosky and Jorge Roberto Ferraris and Jorge A. Ramirez and H{\'e}ctor Jasper and Marco Aurelio Rivarola},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1991},
  volume={73 1},
  pages={107-10}
}
We had previously reported that serum sex hormone binding-globulin (SHBG) decreases and serum non-SHBG-bound testosterone (T) and free T increase significantly from infancy to late prepuberty in normal prepubertal children of both sexes. We had also shown an age-related delay in these changes in hypopituitary boys, which was reversed by GH treatment… CONTINUE READING