Serum sclerostin levels positively correlate with lumbar spinal bone mineral density in postmenopausal women—the six-month effect of risedronate and teriparatide

@article{Polyzos2010SerumSL,
  title={Serum sclerostin levels positively correlate with lumbar spinal bone mineral density in postmenopausal women—the six-month effect of risedronate and teriparatide},
  author={Stergios A Polyzos and Athanasios D Anastasilakis and Cornelia Bratengeier and Wolfgang Woloszczuk and Athanasios Papatheodorou and Evangelos Terpos},
  journal={Osteoporosis International},
  year={2010},
  volume={23},
  pages={1171-1176}
}
Sclerostin is expressed by osteocytes and inhibits bone formation by osteoblasts. In this study, serum sclerostin was positively correlated with either lumbar spinal bone mineral density or T-score. Furthermore, serum sclerostin was increased after 6 months treatment with risedronate, whereas remained unchanged after 6 months teriparatide treatment. The primary aim of this study was the evaluation of serum sclerostin levels in postmenopausal women and their association with bone mineral density… CONTINUE READING
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