Serum samples can be substituted by plasma samples for the diagnosis of paratuberculosis.

@article{Goodridge2013SerumSC,
  title={Serum samples can be substituted by plasma samples for the diagnosis of paratuberculosis.},
  author={Amador Goodridge and Ricardo Henrique Bilycz Correa and Paul C. Castro and Cecilia Escobar and Jacobus Henri de Waard},
  journal={Preventive veterinary medicine},
  year={2013},
  volume={112 1-2},
  pages={147-9}
}
Employing plasma samples rather than serum samples for serological paratuberculosis diagnosis is practical, especially when bovine TB is assessed in the same cattle herd with the gamma interferon bovine avian (IFN-γ BA) test. We demonstrate that antibody titers in serum and plasma samples, utilizing the PARACHECK(®) ELISA kit, are highly comparable (Cohen's kappa test, k=0.955). We conclude that serum can be replaced with plasma in this commercially available antibody detection assay resulting… CONTINUE READING
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