Serum resistance in Haemophilus parasuis SC096 strain requires outer membrane protein P2 expression.

@article{Zhang2012SerumRI,
  title={Serum resistance in Haemophilus parasuis SC096 strain requires outer membrane protein P2 expression.},
  author={Bin Zhang and Saixiang Feng and Chenggang Xu and Suming Zhou and Yanbing He and Lingyun Zhang and Jianmin Zhang and Lili Guo and Ming Xing Liao},
  journal={FEMS microbiology letters},
  year={2012},
  volume={326 2},
  pages={109-15}
}
Haemophilus parasuis outer membrane protein P2 (OmpP2), the most abundant protein in the outer membrane, has been identified as an antigenic protein and a potential virulence factor. To study the precise function of OmpP2, an ompP2-deficient mutant (ΔompP2) of a H. parasuis serovar 4 clinical strain SC096 was constructed by a modified natural transformation system. Compared with the wild-type SC096 strain, the ΔompP2 mutant showed a pronounced growth defect and exhibited significantly greater… CONTINUE READING
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