Serum prolactin concentrations determine whether they improve or impair β-cell function and insulin sensitivity in diabetic rats.

@article{Park2011SerumPC,
  title={Serum prolactin concentrations determine whether they improve or impair β-cell function and insulin sensitivity in diabetic rats.},
  author={Sunmin Park and Da Sol Kim and J. W. Daily and Sung-Hoon Kim},
  journal={Diabetes/metabolism research and reviews},
  year={2011},
  volume={27 6},
  pages={564-74}
}
BACKGROUND Prolactin improves glucose homeostasis by increasing β-cell mass under certain conditions such as pregnancy, whereas hyperprolactinaemia due to a pituitary gland adenoma tumour exacerbates insulin resistance. However, previous studies have not evaluated how prolactin modulates β-cell function and insulin sensitivity at different dosages. Here, we… CONTINUE READING