Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systematic review and meta-analysis.

@article{Simon2004SerumPA,
  title={Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systematic review and meta-analysis.},
  author={Liliana Simon and France Gauvin and Devendra Krishna Amre and Patrick Saint-Louis and Jacques Lacroix},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2004},
  volume={39 2},
  pages={206-17}
}
A meta-analysis was performed to evaluate the accuracy of determination of procalcitonin (PCT) and C-reactive protein (CRP) levels for the diagnosis of bacterial infection. The analysis included published studies that evaluated these markers for the diagnosis of bacterial infections in hospitalized patients. PCT level was more sensitive (88% [95% confidence interval [CI], 80%-93%] vs. 75% [95% CI, 62%-84%]) and more specific (81% [95% CI, 67%-90%] vs. 67% [95% CI, 56%-77%]) than CRP level for… CONTINUE READING
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