Serum neutrophil gelatinase-associated lipocalin as a marker of renal function in children with chronic kidney disease

@article{Mitsnefes2006SerumNG,
  title={Serum neutrophil gelatinase-associated lipocalin as a marker of renal function in children with chronic kidney disease},
  author={Mark M. Mitsnefes and Thelma S. Kathman and Jaya Mishra and Janis Kartal and Philip R. Khoury and Thomas L Nickolas and Jonathan Barasch and Prasad Devarajan},
  journal={Pediatric Nephrology},
  year={2006},
  volume={22},
  pages={101-108}
}
Very few biomarkers exist for monitoring chronic kidney disease (CKD). We have recently shown that serum neutrophil gelatinase-associated lipocalin (NGAL) represents a novel biomarker for early identification of acute kidney injury. In this study, we hypothesized that serum NGAL may also represent a biomarker for the quantitation of CKD. Forty-five children with CKD stages 2–4 were prospectively recruited for measurement of serum NGAL, serum cystatin C, glomerular filtration rate (GFR) by… CONTINUE READING

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